#!/usr/bin/python3 from subprocess import check_call from pathlib import Path home = Path.home() path_to_file = home / 'Pyapps/wire-py/wg_py' with open(path_to_file, 'r') as file: for line in file.readlines(): a_con = line[5:] check_call(['nmcli', 'connection', 'up', a_con])